Martin Kulldorff

Education and Career

Martin Kulldorff obtained a BSc degree in mathematical statistics from Umeå Universitet, Sweden, in 1984. After graduating, he moved to the US as a Fulbright fellow to acquire a PhD in operation research and industrial engineering from Cornell University in 1989. His PhD thesis was dedicated to controlling games with a time limit.

In 1989, Kulldorff served as a Human Rights observer in Guatemala for Peace Brigades International. After Guatemala, He returned to Sweden where he served for 6 years as an assistant professor (5 years) and associate professor of the Department of Statistics at Uppsala University. In 1993-94, he worked as a visiting scientist for the Biometry branch at the National Institute of Neurological Disorders and Stroke, NIH.

In 1995, Kulldorff moved to the US to work at the National Cancer Institute (NCI) as a Scientist at the Biometry Branch, Division of Cancer Prevention. In 1998-2003, Martin has been working as an associate professor of the Department of Community Medicine and adjunct associate professor of the Department of Statistics at the University of Connecticut.

In 2003, Kulldorff joined the Harvard Medical School as a professor. In 2015-21, he worked at Brigham and Women’s Hospital as a professor of Medicine in the Division of Pharmacoepidemiology and Pharmacoeconomics.

Research Interests

Martin Kulldorff’s main research interests lie in developing and applying statistical methods for disease surveillance. He has contributed to the development of statistical and epidemiological methods for the early identification of disease outbreaks and side effects of vaccines and drugs.

His methods and software for scan statistics are well-cited and used in several disciplines to discover geographical clusters and assess whether or not they are due to chance. Kulldorff also uses statistics in a number of different subject areas such as cancer epidemiology, nutritional epidemiology, infectious diseases, vector-borne diseases, antibiotic-resistant bacteria, birth defects, pharmacoepidemiology, vaccine studies, and health research.

Publications

• Yih WK, Kulldorff M, Dashevsky I, Maro JC. Sequential Data-Mining for Adverse Events After Recombinant Herpes Zoster Vaccination Using the Tree-Based Scan Statistic. Am J Epidemiol. 2023 02 01; 192(2):276-282. PMID: 36227263.
• Bhattacharya J, Magness P, Kulldorff M. Understanding the exceptional pre-vaccination Era East Asian COVID-19 outcomes. Adv Biol Regul. 2022 12; 86:100916. PMID: 36328937; PMCID: PMC9575551.
• Miller MB, Ooi EE, Rhoads DD, Kulldorff M, Anderson DE, Lee H, Gupta S, Mel K. As Omicron Takes Hold and Other New Variants Arise, COVID-19 Testing Remains the Universally Agreed Tool to Effect Transition From Pandemic to Endemic State. Front Public Health. 2022; 10:883066. PMID: 35602143; PMCID: PMC9121917.
• Yih WK, Kulldorff M, Dashevsky I, Maro JC. A Broad Safety Assessment of the Recombinant Herpes Zoster Vaccine. Am J Epidemiol. 2022 03 24; 191(5):957-964. PMID: 35152283; PMCID: PMC9071519.
• Shiner B, Forehand JA, Rozema L, Kulldorff M, Watts BV, Trefethen M, Jiang T, Huybrechts KF, Schnurr PP, Vincenti M, Gui J, Gradus JL. Mining Clinical Data for Novel Posttraumatic Stress Disorder Medications. Biol Psychiatry. 2022 04 01; 91(7):647-657. PMID: 34952698; PMCID: PMC8918007.
• Wang SV, Maro JC, Gagne JJ, Patorno E, Kattinakere S, Stojanovic D, Eworuke E, Baro E, Ouellet-Hellstrom R, Nguyen M, Ma Y, Dashevsky I, Cole D, DeLuccia S, Hansbury A, Pestine E, Kulldorff M. A General Propensity Score for Signal Identification Using Tree-Based Scan Statistics. Am J Epidemiol. 2021 07 01; 190(7):1424-1433. PMID: 33615330.
• Yih WK, Kulldorff M, Dashevsky I, Maro JC. A Broad Safety Assessment of the 9-Valent Human Papillomavirus Vaccine. Am J Epidemiol. 2021 07 01; 190(7):1253-1259. PMID: 33558897.
• R Silva I, Maro J, Kulldorff M. Exact sequential test for clinical trials and post-market drug and vaccine safety surveillance with Poisson and binary data. Stat Med. 2021 09 30; 40(22):4890-4913. PMID: 34120357; PMCID: PMC8441767.
• Huybrechts KF, Kulldorff M, Hernández-Díaz S, Bateman BT, Zhu Y, Mogun H, Wang SV. Active Surveillance of the Safety of Medications Used During Pregnancy. Am J Epidemiol. 2021 06 01; 190(6):1159-1168. PMID: 33423046.
• Greene SK, Peterson ER, Balan D, Jones L, Culp GM, Fine AD, Kulldorff M. Detecting COVID-19 Clusters at High Spatiotemporal Resolution, New York City, New York, USA, June-July 2020. Emerg Infect Dis. 2021 05; 27(5). PMID: 33900181; PMCID: PMC8084513.
• Fralick M, Kulldorff M, Redelmeier D, Wang SV, Vine S, Schneeweiss S, Patorno E. A novel data mining application to detect safety signals for newly approved medications in routine care of patients with diabetes. Endocrinol Diabetes Metab. 2021 Jul; 4(3):e00237. PMID: 34277962; PMCID: PMC8279599.
• Kampf G, Kulldorff M. Calling for benefit-risk evaluations of COVID-19 control measures. Lancet. 2021 02 13; 397(10274):576-577. PMID: 33549169; PMCID: PMC7906630.
• Baral S, Chandler R, Prieto RG, Gupta S, Mishra S, Kulldorff M. Leveraging epidemiological principles to evaluate Sweden’s COVID-19 response. Ann Epidemiol. 2021 02; 54:21-26. PMID: 33242596.
• Kesselheim AS, Darrow JJ, Kulldorff M, Brown BL, Mitra-Majumdar M, Lee CC, Moneer O, Avorn J. An Overview Of Vaccine Development, Approval, And Regulation, With Implications For COVID-19. Health Aff (Millwood). 2021 01; 40(1):25-32. PMID: 33211535.
• Zerbo O, Ray GT, Zhang L, Goddard K, Fireman B, Adams A, Omer S, Kulldorff M, Klein NP. Individual and Neighborhood Factors Associated With Failure to Vaccinate Against Influenza During Pregnancy. Am J Epidemiol. 2020 11 02; 189(11):1379-1388. PMID: 32735018; PMCID: PMC7604527.
• Wintzell V, Svanström H, Melbye M, Ludvigsson JF, Pasternak B, Kulldorff M. Data Mining for Adverse Events of Tumor Necrosis Factor-Alpha Inhibitors in Pediatric Patients: Tree-Based Scan Statistic Analyses of Danish Nationwide Health Data. Clin Drug Investig. 2020 Dec; 40(12):1147-1154. PMID: 33104987.
• Wang SV, Stefanini K, Lewis E, Newcomer SR, Fireman B, Daley MF, Glanz JM, Duffy J, Weintraub E, Kulldorff M. Determining Which of Several Simultaneously Administered Vaccines Increase Risk of an Adverse Event. Drug Saf. 2020 10; 43(10):1057-1065. PMID: 32613596.
• Wang SV, Kulldorff M, Poor S, Rice DS, Banks A, Li N, Lii J, Gagne JJ. Screening Medications for Association with Progression to Wet Age-Related Macular Degeneration. Ophthalmology. 2021 02; 128(2):248-255. PMID: 32777229.
• Baker MA, Yokoe DS, Stelling J, Kleinman K, Kaganov RE, Letourneau AR, Varma N, O’Brien T, Kulldorff M, Babalola D, Barrett C, Drees M, Coady MH, Isaacs A, Platt R, Huang SS. Automated outbreak detection of hospital-associated pathogens: Value to infection prevention programs. Infect Control Hosp Epidemiol. 2020 09; 41(9):1016-1021. PMID: 32519624; PMCID: PMC9451926.
• Yih WK, Kulldorff M, Leibler JH, Friedman DJ, Brooks DR. Comment on Sarathkumara et al.: Exposure to Hantavirus is a Risk Factor Associated with Kidney Diseases in Sri Lanka: A Cross Sectional Study. Viruses. 2019 12 11; 11(12). PMID: 31835714.
• Newcomer SR, Xu S, Kulldorff M, Daley MF, Fireman B, Glanz JM. A primer on quantitative bias analysis with positive predictive values in research using electronic health data. J Am Med Inform Assoc. 2019 12 01; 26(12):1664-1674. PMID: 31365086.
• Patorno E, Najafzadeh M, Pawar A, Franklin JM, Déruaz-Luyet A, Brodovicz KG, Santiago Ortiz AJ, Bessette LG, Kulldorff M, Schneeweiss S. The EMPagliflozin compaRative effectIveness and SafEty (EMPRISE) study programme: Design and exposure accrual for an evaluation of empagliflozin in routine clinical care. Endocrinol Diabetes Metab. 2020 Jan; 3(1):e00103. PMID: 31922030; PMCID: PMC6947693.
• Silva IR, Gagne JJ, Najafzadeh M, Kulldorff M. Exact sequential analysis for multiple weighted binomial end points. Stat Med. 2020 02 10; 39(3):340-351. PMID: 31769079.
• Luo J, Kulldorff M, Sarpatwari A, Pawar A, Kesselheim AS. Variation in Prescription Drug Prices by Retail Pharmacy Type: A National Cross-sectional Study. Ann Intern Med. 2019 11 05; 171(9):605-611. PMID: 31569218.
• Yih WK, Kulldorff M, Friedman DJ, Leibler JH, Amador JJ, López-Pilarte D, Galloway RL, Ramírez-Rubio O, Riefkohl A, Brooks DR. Investigating Possible Infectious Causes of Chronic Kidney Disease of Unknown Etiology in a Nicaraguan Mining Community. Am J Trop Med Hyg. 2019 09; 101(3):676-683. PMID: 31309920; PMCID: PMC6726956.
• Baker MA, Baer B, Kulldorff M, Zichittella L, Reindel R, DeLuccia S, Lipowicz H, Freitas K, Jin R, Yih WK. Kawasaki disease and 13-valent pneumococcal conjugate vaccination among young children: A self-controlled risk interval and cohort study with null results. PLoS Med. 2019 07; 16(7):e1002844. PMID: 31265459.
• Yih WK, Kulldorff M, Dashevsky I, Maro JC. Using the Self-Controlled Tree-Temporal Scan Statistic to Assess the Safety of Live Attenuated Herpes Zoster Vaccine. Am J Epidemiol. 2019 07 01; 188(7):1383-1388. PMID: 31062840.
• Silva IR, Li L, Kulldorff M. Exact conditional maximized sequential probability ratio test adjusted for covariates. Seq Anal. 2019; 38(1):115-133. PMID: 32153315; PMCID: PMC7061912.
• Ray GT, Lewis N, Klein NP, Daley MF, Wang SV, Kulldorff M, Fireman B. Intraseason Waning of Influenza Vaccine Effectiveness. Clin Infect Dis. 2019 05 02; 68(10):1623-1630. PMID: 30204855; PMCID: PMC7182205.
• Patorno E, Gopalakrishnan C, Brodovicz KG, Meyers A, Bartels DB, Liu J, Kulldorff M, Schneeweiss S. Cardiovascular safety of linagliptin compared with other oral glucose-lowering agents in patients with type 2 diabetes: A sequential monitoring programme in routine care. Diabetes Obes Metab. 2019 08; 21(8):1824-1836. PMID: 30941884.
• Patorno E, Pawar A, Franklin JM, Najafzadeh M, Déruaz-Luyet A, Brodovicz KG, Sambevski S, Bessette LG, Santiago Ortiz AJ, Kulldorff M, Schneeweiss S. Empagliflozin and the Risk of Heart Failure Hospitalization in Routine Clinical Care. Circulation. 2019 06 18; 139(25):2822-2830. PMID: 30955357; PMCID: PMC6594384.
• Schneeweiss S, Gopalakrishnan C, Bartels DB, Franklin JM, Zint K, Kulldorff M, Huybrechts KF. Sequential Monitoring of the Comparative Effectiveness and Safety of Dabigatran in Routine Care. Circ Cardiovasc Qual Outcomes. 2019 02; 12(2):e005173. PMID: 30764655.
• Xu S, Newcomer SR, Kulldorff M, Daley MF, Fireman B, Glanz JM. Use of three summary measures of pediatric vaccination for studying the safety of the childhood immunization schedule. Vaccine. 2019 02 28; 37(10):1325-1331. PMID: 30709727.
• Wang SV, Maro JC, Baro E, Izem R, Dashevsky I, Rogers JR, Nguyen M, Gagne JJ, Patorno E, Huybrechts KF, Major JM, Zhou E, Reidy M, Cosgrove A, Schneeweiss S, Kulldorff M. Data Mining for Adverse Drug Events With a Propensity Score-matched Tree-based Scan Statistic. Epidemiology. 2018 11; 29(6):895-903. PMID: 30074538.
• Yih WK, Maro JC, Nguyen M, Baker MA, Balsbaugh C, Cole DV, Dashevsky I, Mba-Jonas A, Kulldorff M. Assessment of Quadrivalent Human Papillomavirus Vaccine Safety Using the Self-Controlled Tree-Temporal Scan Statistic Signal-Detection Method in the Sentinel System. Am J Epidemiol. 2018 06 01; 187(6):1269-1276. PMID: 29860470; PMCID: PMC5982709.
• Yih WK, Maro JC, Kulldorff M. Yih et al. Respond to “Moving From Evidence to Impact for Human Papillomavirus Vaccination”. Am J Epidemiol. 2018 06 01; 187(6):1281. PMID: 29860469.
• Lu CY, Simon G, Soumerai SB, Kulldorff M. Counter-Point: Early Warning Systems Are Imperfect, but Essential. Med Care. 2018 05; 56(5):382-383. PMID: 29634630.
• Lu CY, Penfold RB, Toh S, Sturtevant JL, Madden JM, Simon G, Ahmedani BK, Clarke G, Coleman KJ, Copeland LA, Daida YG, Davis RL, Hunkeler EM, Owen-Smith A, Raebel MA, Rossom R, Soumerai SB, Kulldorff M. Near Real-time Surveillance for Consequences of Health Policies Using Sequential Analysis. Med Care. 2018 05; 56(5):365-372. PMID: 29634627.
• Wang SV, Kulldorff M, Glynn RJ, Gagne JJ, Pottegård A, Rothman KJ, Schneeweiss S, Walker AM. Reuse of data sources to evaluate drug safety signals: When is it appropriate? Pharmacoepidemiol Drug Saf. 2018 06; 27(6):567-569. PMID: 29701279.
• Oliveira FLP, Cançado ALF, de Souza G, Moreira GJP, Kulldorff M. Border analysis for spatial clusters. Int J Health Geogr. 2018 02 17; 17(1):5. PMID: 29454357.
• Li R, Weintraub E, McNeil MM, Kulldorff M, Lewis EM, Nelson J, Xu S, Qian L, Klein NP, Destefano F. Meningococcal conjugate vaccine safety surveillance in the Vaccine Safety Datalink using a tree-temporal scan data mining method. Pharmacoepidemiol Drug Saf. 2018 04; 27(4):391-397. PMID: 29446176.
• Wang SV, Abdurrob A, Spoendlin J, Lewis E, Newcomer SR, Fireman B, Daley MF, Glanz JM, Duffy J, Weintraub ES, Kulldorff M. Methods for addressing “innocent bystanders” when evaluating safety of concomitant vaccines. Pharmacoepidemiol Drug Saf. 2018 04; 27(4):405-412. PMID: 29441647.
• Newcomer SR, Kulldorff M, Xu S, Daley MF, Fireman B, Lewis E, Glanz JM. Bias from outcome misclassification in immunization schedule safety research. Pharmacoepidemiol Drug Saf. 2018 02; 27(2):221-228. PMID: 29292551.
• Krumme AA, Pawar A, Schneeweiss S, Glynn RJ, Choudhry NK, Kulldorff M, Ortiz AS, Avorn J, Gagne JJ. Study protocol for the dabigatran, apixaban, rivaroxaban, edoxaban, warfarin comparative effectiveness research study. J Comp Eff Res. 2018 01; 7(1):57-66. PMID: 29264930.
• Wehner MR, Levandoski KA, Kulldorff M, Asgari MM. Research Techniques Made Simple: An Introduction to Use and Analysis of Big Data in Dermatology. J Invest Dermatol. 2017 08; 137(8):e153-e158. PMID: 28735616; PMCID: PMC5600502.
• Kulldorff M, Silva IR. Continuous Post-Market Sequential Safety Surveillance with Minimum Events to Signal. Revstat Stat J. 2017 Jul; 15(3):373-394. PMID: 34393695; PMCID: PMC8363220.
• Aloe C, Kulldorff M, Bloom BR. Geospatial analysis of nonmedical vaccine exemptions and pertussis outbreaks in the United States. Proc Natl Acad Sci U S A. 2017 07 03; 114(27):7101-7105. PMID: 28634290; PMCID: PMC5502604.
• Maro JC, Nguyen MD, Dashevsky I, Baker MA, Kulldorff M. Statistical Power for Postlicensure Medical Product Safety Data Mining. EGEMS (Wash DC). 2017 Jun 12; 5(1):6. PMID: 29881732; PMCID: PMC5982804.
• Sridhar G, Tian F, Forshee R, Kulldorff M, Selvam N, Sutherland A, Bryan W, Barone S, Xu L, Izurieta HS. Evaluation of optic neuritis following human papillomavirus vaccination. Hum Vaccin Immunother. 2017 07 03; 13(7):1705-1713. PMID: 28463636.
• Franklin JM, Dejene S, Huybrechts KF, Wang SV, Kulldorff M, Rothman KJ. A Bias in the Evaluation of Bias Comparing Randomized Trials with Nonexperimental Studies. Epidemiol Methods. 2017 Apr; 6(1). PMID: 29204330; PMCID: PMC5710821.
• Ray GT, Kulldorff M, Asgari MM. Geographic Clusters of Basal Cell Carcinoma in a Northern California Health Plan Population. JAMA Dermatol. 2016 11 01; 152(11):1218-1224. PMID: 27439152; PMCID: PMC6333304.
• Greene SK, Peterson ER, Kapell D, Fine AD, Kulldorff M. Daily Reportable Disease Spatiotemporal Cluster Detection, New York City, New York, USA, 2014-2015. Emerg Infect Dis. 2016 10; 22(10):1808-12. PMID: 27648777; PMCID: PMC5038417.
• Park R, O’Brien TF, Huang SS, Baker MA, Yokoe DS, Kulldorff M, Barrett C, Swift J, Stelling J. Statistical detection of geographic clusters of resistant Escherichia coli in a regional network with WHONET and SaTScan. Expert Rev Anti Infect Ther. 2016 11; 14(11):1097-1107. PMID: 27530311; PMCID: PMC5109973.
• Han J, Zhu L, Kulldorff M, Hostovich S, Stinchcomb DG, Tatalovich Z, Lewis DR, Feuer EJ. Using Gini coefficient to determining optimal cluster reporting sizes for spatial scan statistics. Int J Health Geogr. 2016 08 03; 15(1):27. PMID: 27488416.
• Duncan DT, Rienti M, Kulldorff M, Aldstadt J, Castro MC, Frounfelker R, Williams JH, Sorensen G, Johnson RM, Hemenway D, Williams DR. Local spatial clustering in youths’ use of tobacco, alcohol, and marijuana in Boston. Am J Drug Alcohol Abuse. 2016 07; 42(4):412-21. PMID: 27096932.
• Boscoe FP, Talbot TO, Kulldorff M. Public domain small-area cancer incidence data for New York State, 2005-2009. Geospat Health. 2016 Apr 18; 11(1):304. PMID: 27087033; PMCID: PMC5544011.
• Yih WK, Kulldorff M, Sandhu SK, Zichittella L, Maro JC, Cole DV, Jin R, Kawai AT, Baker MA, Liu C, McMahill-Walraven CN, Selvan MS, Platt R, Nguyen MD, Lee GM. Prospective influenza vaccine safety surveillance using fresh data in the Sentinel System. Pharmacoepidemiol Drug Saf. 2016 05; 25(5):481-92. PMID: 26572776.
• Yih WK, Greene SK, Zichittella L, Kulldorff M, Baker MA, de Jong JL, Gil-Prieto R, Griffin MR, Jin R, Lin ND, McMahill-Walraven CN, Reidy M, Selvam N, Selvan MS, Nguyen MD. Evaluation of the risk of venous thromboembolism after quadrivalent human papillomavirus vaccination among US females. Vaccine. 2016 Jan 02; 34(1):172-8. PMID: 26549364.
• Li L, Kulldorff M, Russek-Cohen E, Kawai AT, Hua W. Quantifying the impact of time-varying baseline risk adjustment in the self-controlled risk interval design. Pharmacoepidemiol Drug Saf. 2015 Dec; 24(12):1304-12. PMID: 26464236.
• Amin R, Nabors NS, Nelson AM, Saqlain M, Kulldorff M. Geographical Clusters of Rape in the United States: 2000-2012. Stat Public Policy (Phila). 2015; 2(1):87-92. PMID: 28078318; PMCID: PMC5221697.
• Kawai AT, Martin D, Kulldorff M, Li L, Cole DV, McMahill-Walraven CN, Selvam N, Selvan MS, Lee GM. Febrile Seizures After 2010-2011 Trivalent Inactivated Influenza Vaccine. Pediatrics. 2015 Oct; 136(4):e848-55. PMID: 26371192.
• Silva IR, Kulldorff M. Continuous versus group sequential analysis for post-market drug and vaccine safety surveillance. Biometrics. 2015 Sep; 71(3):851-8. PMID: 26011024.Kulldorff M, Kleinman K. Comments on ‘a critical look at prospective surveillance using a scan statistic’ by T. Correa, M. Costa, and R. Assunção. Stat Med. 2015 Mar 30; 34(7):1094-5. PMID: 25754922; PMCID: PMC4357279.
• Lieu TA, Ray GT, Klein NP, Chung C, Kulldorff M. Geographic clusters in underimmunization and vaccine refusal. Pediatrics. 2015 Feb; 135(2):280-9. PMID: 25601971.
• Davison KK, Falbe J, Taveras EM, Gortmaker S, Kulldorff M, Perkins M, Blaine RE, Franckle RL, Ganter C, Woo Baidal J, Kwass JA, Buszkiewicz J, Smith L, Land T. Evaluation overview for the Massachusetts Childhood Obesity Research Demonstration (MA-CORD) project. Child Obes. 2015 02; 11(1):23-36. PMID: 25575095.
• Costa MA, Kulldorff M. Maximum linkage space-time permutation scan statistics for disease outbreak detection. Int J Health Geogr. 2014 Jun 10; 13:20. PMID: 24916839.
• Maro JC, Brown JS, Dal Pan GJ, Kulldorff M. Minimizing signal detection time in postmarket sequential analysis: balancing positive predictive value and sensitivity. Pharmacoepidemiol Drug Saf. 2014 Aug; 23(8):839-48. PMID: 24700557.
• Prates MO, Kulldorff M, Assunção RM. Relative risk estimates from spatial and space-time scan statistics: are they biased? Stat Med. 2014 Jul 10; 33(15):2634-44. PMID: 24639031.
• Kawai AT, Li L, Kulldorff M, Vellozzi C, Weintraub E, Baxter R, Belongia EA, Daley MF, Jacobsen SJ, Naleway A, Nordin JD, Lee GM. Absence of associations between influenza vaccines and increased risks of seizures, Guillain-Barré syndrome, encephalitis, or anaphylaxis in the 2012-2013 season. Pharmacoepidemiol Drug Saf. 2014 May; 23(5):548-53. PMID: 24497128.
• Yih WK, Lieu TA, Kulldorff M, Martin D, McMahill-Walraven CN, Platt R, Selvam N, Selvan M, Lee GM, Nguyen M. Intussusception risk after rotavirus vaccination in U.S. infants. N Engl J Med. 2014 Feb 06; 370(6):503-12. PMID: 24422676.
• Yih WK, Cocoros NM, Crockett M, Klompas M, Kruskal BA, Kulldorff M, Lazarus R, Madoff LC, Morrison MJ, Smole S, Platt R. Automated influenza-like illness reporting–an efficient adjunct to traditional sentinel surveillance. Public Health Rep. 2014 Jan-Feb; 129(1):55-63. PMID: 24381360; PMCID: PMC3863004.
• Galar A, Kulldorff M, Rudnick W, O’Brien TF, Stelling J. Biochemical phenotypes to discriminate microbial subpopulations and improve outbreak detection. PLoS One. 2013; 8(12):e84313. PMID: 24391936.
• Viñas MR, Tuduri E, Galar A, Yih K, Pichel M, Stelling J, Brengi SP, Della Gaspera A, van der Ploeg C, Bruno S, Rogé A, Caffer MI, Kulldorff M, Galas M. Laboratory-based prospective surveillance for community outbreaks of Shigella spp. in Argentina. PLoS Negl Trop Dis. 2013; 7(12):e2521. PMID: 24349586.
• Maro JC, Brown JS, Kulldorff M. Medical product safety surveillance: how many databases to use? Epidemiology. 2013 Sep; 24(5):692-9. PMID: 23867812.
• Toh S, Gagne JJ, Rassen JA, Fireman BH, Kulldorff M, Brown JS. Confounding adjustment in comparative effectiveness research conducted within distributed research networks. Med Care. 2013 Aug; 51(8 Suppl 3):S4-10. PMID: 23752258.
• Greene SK, Rett MD, Vellozzi C, Li L, Kulldorff M, Marcy SM, Daley MF, Belongia EA, Baxter R, Fireman BH, Jackson ML, Omer SB, Nordin JD, Jin R, Weintraub ES, Vijayadeva V, Lee GM. Guillain-Barré Syndrome, Influenza Vaccination, and Antecedent Respiratory and Gastrointestinal Infections: A Case-Centered Analysis in the Vaccine Safety Datalink, 2009-2011. PLoS One. 2013; 8(6):e67185. PMID: 23840621.
• Moraga P, Kulldorff M. Detection of spatial variations in temporal trends with a quadratic function. Stat Methods Med Res. 2016 08; 25(4):1422-37. PMID: 23613491.
• Kulldorff M, Dashevsky I, Avery TR, Chan AK, Davis RL, Graham D, Platt R, Andrade SE, Boudreau D, Gunter MJ, Herrinton LJ, Pawloski PA, Raebel MA, Roblin D, Brown JS. Drug safety data mining with a tree-based scan statistic. Pharmacoepidemiol Drug Saf. 2013 May; 22(5):517-23. PMID: 23512870.
• Brown JS, Petronis KR, Bate A, Zhang F, Dashevsky I, Kulldorff M, Avery TR, Davis RL, Chan KA, Andrade SE, Boudreau D, Gunter MJ, Herrinton L, Pawloski PA, Raebel MA, Roblin D, Smith D, Reynolds R. Drug Adverse Event Detection in Health Plan Data Using the Gamma Poisson Shrinker and Comparison to the Tree-based Scan Statistic. Pharmaceutics. 2013 Mar 14; 5(1):179-200. PMID: 24300404.
• Avery TR, Kulldorff M, Vilk Y, Li L, Cheetham TC, Dublin S, Davis RL, Liu L, Herrinton L, Brown JS. Near real-time adverse drug reaction surveillance within population-based health networks: methodology considerations for data accrual. Pharmacoepidemiol Drug Saf. 2013 May; 22(5):488-95. PMID: 23401239.
• Yih WK, Weintraub E, Kulldorff M. No risk of Guillain-Barré syndrome found after meningococcal conjugate vaccination in two large cohort studies. Pharmacoepidemiol Drug Saf. 2012 Dec; 21(12):1359-60. PMID: 23225672.
• Jones SG, Kulldorff M. Influence of spatial resolution on space-time disease cluster detection. PLoS One. 2012; 7(10):e48036. PMID: 23110167.
• Yih WK, Lee GM, Lieu TA, Ball R, Kulldorff M, Rett M, Wahl PM, McMahill-Walraven CN, Platt R, Salmon DA. Surveillance for adverse events following receipt of pandemic 2009 H1N1 vaccine in the Post-Licensure Rapid Immunization Safety Monitoring (PRISM) System, 2009-2010. Am J Epidemiol. 2012 Jun 01; 175(11):1120-8. PMID: 22582207.
• Greene SK, Rett M, Weintraub ES, Li L, Yin R, Amato AA, Ho DT, Sheikh SI, Fireman BH, Daley MF, Belongia EA, Jacobsen SJ, Baxter R, Lieu TA, Kulldorff M, Vellozzi C, Lee GM. Risk of confirmed Guillain-Barre syndrome following receipt of monovalent inactivated influenza A (H1N1) and seasonal influenza vaccines in the Vaccine Safety Datalink Project, 2009-2010. Am J Epidemiol. 2012 Jun 01; 175(11):1100-9. PMID: 22582210.
• Greene SK, Huang J, Abrams AM, Gilliss D, Reed M, Platt R, Huang SS, Kulldorff M. Gastrointestinal disease outbreak detection using multiple data streams from electronic medical records. Foodborne Pathog Dis. 2012 May; 9(5):431-41. PMID: 22429155.
• Klompas M, Kulldorff M, Vilk Y, Bialek SR, Harpaz R. Herpes zoster and postherpetic neuralgia surveillance using structured electronic data. Mayo Clin Proc. 2011 Dec; 86(12):1146-53. PMID: 21997577; PMCID: PMC3228613.
• Gee J, Naleway A, Shui I, Baggs J, Yin R, Li R, Kulldorff M, Lewis E, Fireman B, Daley MF, Klein NP, Weintraub ES. Monitoring the safety of quadrivalent human papillomavirus vaccine: findings from the Vaccine Safety Datalink. Vaccine. 2011 Oct 26; 29(46):8279-84. PMID: 21907257.
• Lee GM, Greene SK, Weintraub ES, Baggs J, Kulldorff M, Fireman BH, Baxter R, Jacobsen SJ, Irving S, Daley MF, Yin R, Naleway A, Nordin JD, Li L, McCarthy N, Vellozzi C, Destefano F, Lieu TA. H1N1 and seasonal influenza vaccine safety in the vaccine safety datalink project. Am J Prev Med. 2011 Aug; 41(2):121-8. PMID: 21767718.
• Greene SK, Kulldorff M, Yin R, Yih WK, Lieu TA, Weintraub ES, Lee GM. Near real-time vaccine safety surveillance with partially accrued data. Pharmacoepidemiol Drug Saf. 2011 Jun; 20(6):583-90. PMID: 21538670.
• Costa MA, Huang SS, Moore M, Kulldorff M, Finkelstein JA. New approaches to estimating national rates of invasive pneumococcal disease. Am J Epidemiol. 2011 Jul 15; 174(2):234-42. PMID: 21617259.
• Yih WK, Kulldorff M, Fireman BH, Shui IM, Lewis EM, Klein NP, Baggs J, Weintraub ES, Belongia EA, Naleway A, Gee J, Platt R, Lieu TA. Active surveillance for adverse events: the experience of the Vaccine Safety Datalink project. Pediatrics. 2011 May; 127 Suppl 1:S54-64. PMID: 21502252.
• Greene SK, Kulldorff M, Huang J, Brand RJ, Kleinman KP, Hsu J, Platt R. Timely detection of localized excess influenza activity in Northern California across patient care, prescription, and laboratory data. Stat Med. 2011 Feb 28; 30(5):549-59. PMID: 21312219.
• Abrams AM, Kleinman K, Kulldorff M. Gumbel based p-value approximations for spatial scan statistics. Int J Health Geogr. 2010 Dec 17; 9:61. PMID: 21167043.
• Nordin JD, Yih WK, Kulldorff M, Weintraub E. Tdap and GBS letter. Vaccine. 2011 Feb 01; 29(6):1122. PMID: 21130193.
• Puett R, Lawson A, Clark A, Hebert J, Kulldorff M. Power Evaluation of Focused Cluster Tests. Environ Ecol Stat. 2010 Sep; 17(3):303-316. PMID: 24872726.
• Jung I, Kulldorff M, Richard OJ. A spatial scan statistic for multinomial data. Stat Med. 2010 Aug 15; 29(18):1910-8. PMID: 20680984.
• Klein NP, Fireman B, Yih WK, Lewis E, Kulldorff M, Ray P, Baxter R, Hambidge S, Nordin J, Naleway A, Belongia EA, Lieu T, Baggs J, Weintraub E. Measles-mumps-rubella-varicella combination vaccine and the risk of febrile seizures. Pediatrics. 2010 Jul; 126(1):e1-8. PMID: 20587679.
• Huang SS, Yokoe DS, Stelling J, Placzek H, Kulldorff M, Kleinman K, O’Brien TF, Calderwood MS, Vostok J, Dunn J, Platt R. Automated detection of infectious disease outbreaks in hospitals: a retrospective cohort study. PLoS Med. 2010 Feb 23; 7(2):e1000238. PMID: 20186274.
• Curriero FC, Kulldorff M, Boscoe FP, Klassen AC. Using imputation to provide location information for nongeocoded addresses. PLoS One. 2010 Feb 10; 5(2):e8998. PMID: 20161766.
• Li L, Kulldorff M. A conditional maximized sequential probability ratio test for pharmacovigilance. Stat Med. 2010 Jan 30; 29(2):284-95. PMID: 19941282.
• Belongia EA, Irving SA, Shui IM, Kulldorff M, Lewis E, Yin R, Lieu TA, Weintraub E, Yih WK, Li R, Baggs J. Real-time surveillance to assess risk of intussusception and other adverse events after pentavalent, bovine-derived rotavirus vaccine. Pediatr Infect Dis J. 2010 Jan; 29(1):1-5. PMID: 19907356.
• Yih WK, Deshpande S, Fuller C, Heisey-Grove D, Hsu J, Kruskal BA, Kulldorff M, Leach M, Nordin J, Patton-Levine J, Puga E, Sherwood E, Shui I, Platt R. Evaluating real-time syndromic surveillance signals from ambulatory care data in four states. Public Health Rep. 2010 Jan-Feb; 125(1):111-20. PMID: 20402203; PMCID: PMC2789823.
• Greene SK, Kulldorff M, Lewis EM, Li R, Yin R, Weintraub ES, Fireman BH, Lieu TA, Nordin JD, Glanz JM, Baxter R, Jacobsen SJ, Broder KR, Lee GM. Near real-time surveillance for influenza vaccine safety: proof-of-concept in the Vaccine Safety Datalink Project. Am J Epidemiol. 2010 Jan 15; 171(2):177-88. PMID: 19965887.
• Brown JS, Moore KM, Braun MM, Ziyadeh N, Chan KA, Lee GM, Kulldorff M, Walker AM, Platt R. Active influenza vaccine safety surveillance: potential within a healthcare claims environment. Med Care. 2009 Dec; 47(12):1251-7. PMID: 19786905.
• Kulldorff M, Huang L, Konty K. A scan statistic for continuous data based on the normal probability model. Int J Health Geogr. 2009 Oct 20; 8:58. PMID: 19843331.
• Stelling J, Yih WK, Galas M, Kulldorff M, Pichel M, Terragno R, Tuduri E, Espetxe S, Binsztein N, O’Brien TF, Platt R. Automated use of WHONET and SaTScan to detect outbreaks of Shigella spp. using antimicrobial resistance phenotypes. Epidemiol Infect. 2010 Jun; 138(6):873-83. PMID: 19796449.
• Hinrichsen VL, Klassen AC, Song C, Kulldorff M. Evaluation of the performance of tests for spatial randomness on prostate cancer data. Int J Health Geogr. 2009 Jul 03; 8:41. PMID: 19575788.
• O’Brien MA, Prosser LA, Paradise JL, Ray GT, Kulldorff M, Kurs-Lasky M, Hinrichsen VL, Mehta J, Colborn DK, Lieu TA. New vaccines against otitis media: projected benefits and cost-effectiveness. Pediatrics. 2009 Jun; 123(6):1452-63. PMID: 19482754.
• Yih WK, Nordin JD, Kulldorff M, Lewis E, Lieu TA, Shi P, Weintraub ES. An assessment of the safety of adolescent and adult tetanus-diphtheria-acellular pertussis (Tdap) vaccine, using active surveillance for adverse events in the Vaccine Safety Datalink. Vaccine. 2009 Jul 09; 27(32):4257-62. PMID: 19486957.
• Jung I, Kulldorff M, Kleinman KP, Yih WK, Platt R. Using encounters versus episodes in syndromic surveillance. J Public Health (Oxf). 2009 Dec; 31(4):566-72. PMID: 19443438.
• Yih WK, Teates KS, Abrams A, Kleinman K, Kulldorff M, Pinner R, Harmon R, Wang S, Platt R. Telephone triage service data for detection of influenza-like illness. PLoS One. 2009; 4(4):e5260. PMID: 19381342.
• Brown JS, Kulldorff M, Petronis KR, Reynolds R, Chan KA, Davis RL, Graham D, Andrade SE, Raebel MA, Herrinton L, Roblin D, Boudreau D, Smith D, Gurwitz JH, Gunter MJ, Platt R. Early adverse drug event signal detection within population-based health networks using sequential methods: key methodologic considerations. Pharmacoepidemiol Drug Saf. 2009 Mar; 18(3):226-34. PMID: 19148879.
• Fortinsky RH, Kulldorff M, Kleppinger A, Kenyon-Pesce L. Dementia care consultation for family caregivers: collaborative model linking an Alzheimer’s association chapter with primary care physicians. Aging Ment Health. 2009 Mar; 13(2):162-70. PMID: 19347683.
• Klompas M, Kulldorff M, Platt R. Risk of misleading ventilator-associated pneumonia rates with use of standard clinical and microbiological criteria. Clin Infect Dis. 2008 May 01; 46(9):1443-6. PMID: 18419450.
• Takahashi K, Kulldorff M, Tango T, Yih K. A flexibly shaped space-time scan statistic for disease outbreak detection and monitoring. Int J Health Geogr. 2008 Apr 11; 7:14. PMID: 18402711.
• Recuenco S, Eidson M, Cherry B, Kulldorff M, Johnson G. Factors associated with endemic raccoon (Procyon lotor) rabies in terrestrial mammals in New York State, USA. Prev Vet Med. 2008 Aug 15; 86(1-2):30-42. PMID: 18406482.
• Bellantonio S, Kenny AM, Fortinsky RH, Kleppinger A, Robison J, Gruman C, Kulldorff M, Trella PM. Efficacy of a geriatrics team intervention for residents in dementia-specific assisted living facilities: effect on unanticipated transitions. J Am Geriatr Soc. 2008 Mar; 56(3):523-8. PMID: 18179497.
• Brown JS, Kulldorff M, Chan KA, Davis RL, Graham D, Pettus PT, Andrade SE, Raebel MA, Herrinton L, Roblin D, Boudreau D, Smith D, Gurwitz JH, Gunter MJ, Platt R. Early detection of adverse drug events within population-based health networks: application of sequential testing methods. Pharmacoepidemiol Drug Saf. 2007 Dec; 16(12):1275-84. PMID: 17955500.
• Lieu TA, Kulldorff M, Davis RL, Lewis EM, Weintraub E, Yih K, Yin R, Brown JS, Platt R. Real-time vaccine safety surveillance for the early detection of adverse events. Med Care. 2007 Oct; 45(10 Supl 2):S89-95. PMID: 17909389.
• Gregorio DI, Huang L, DeChello LM, Samociuk H, Kulldorff M. Place of residence effect on likelihood of surviving prostate cancer. Ann Epidemiol. 2007 Jul; 17(7):520-4. PMID: 17448679.
• Rolka H, Burkom H, Cooper GF, Kulldorff M, Madigan D, Wong WK. Issues in applied statistics for public health bioterrorism surveillance using multiple data streams: research needs. Stat Med. 2007 Apr 15; 26(8):1834-56. PMID: 17221940.
• Kulldorff M, Mostashari F, Duczmal L, Katherine Yih W, Kleinman K, Platt R. Multivariate scan statistics for disease surveillance. Stat Med. 2007 Apr 15; 26(8):1824-33. PMID: 17216592.
• Recuenco S, Eidson M, Kulldorff M, Johnson G, Cherry B. Spatial and temporal patterns of enzootic raccoon rabies adjusted for multiple covariates. Int J Health Geogr. 2007 Apr 11; 6:14. PMID: 17428324.
• Jung I, Kulldorff M, Klassen AC. A spatial scan statistic for ordinal data. Stat Med. 2007 Mar 30; 26(7):1594-607. PMID: 16795130.
• Huang L, Kulldorff M, Gregorio D. A spatial scan statistic for survival data. Biometrics. 2007 Mar; 63(1):109-18. PMID: 17447935.
• Gunter MJ, Divi RL, Kulldorff M, Vermeulen R, Haverkos KJ, Kuo MM, Strickland P, Poirier MC, Rothman N, Sinha R. Leukocyte polycyclic aromatic hydrocarbon-DNA adduct formation and colorectal adenoma. Carcinogenesis. 2007 Jul; 28(7):1426-9. PMID: 17277232.
• Ward MH, Cross AJ, Divan H, Kulldorff M, Nowell-Kadlubar S, Kadlubar FF, Sinha R. Processed meat intake, CYP2A6 activity and risk of colorectal adenoma. Carcinogenesis. 2007 Jun; 28(6):1210-6. PMID: 17277235.
• Assuncao R, Tavares AI, Correa T, Kulldorff M. Space-time cluster identification in point processes. Canadian Journal of Statistics. 2007; 35:9-25.
• Lawson AB, Simeon S, Kulldorff M, Biggeri A, Magnani C. Line and point cluster models for spatial health data. Computational Statistics and Data Analysis. 2007; 51:6027-6043.
• Jung I, Kulldorff M. Theoretical foundations of tests for spatial randomness. Canadian Journal of Statistics. 2007; 14:433-446.
• Kulldorff M, Huang L, Pickle L, Duczmal L. An elliptic spatial scan statistic. Stat Med. 2006 Nov 30; 25(22):3929-43. PMID: 16435334.
• Bilker W, Gogolak V, Goldsmith D, Hauben M, Herrera G, Hochberg A, Jolley S, Kulldorff M, Madigan D, Nelson R, Shapiro A, Shmueli G. Accelerating statistical research in drug safety. Pharmacoepidemiol Drug Saf. 2006 Sep; 15(9):687-8. PMID: 16941519.
• Kleinman K, Abrams A, Katherine Yih W, Platt R, Kulldorff M. Evaluating spatial surveillance: detection of known outbreaks in real data. Stat Med. 2006 Mar 15; 25(5):755-69. PMID: 16453375.
• Song C, Kulldorff M. Likelihood based tests for spatial randomness. Stat Med. 2006 Mar 15; 25(5):825-39. PMID: 16453369.
• Kulldorff M, Song C, Gregorio D, Samociuk H, DeChello L. Cancer map patterns: are they random or not? Am J Prev Med. 2006 Feb; 30(2 Suppl):S37-49. PMID: 16458789.
• Rusiecki JA, Kulldorff M, Nuckols JR, Song C, Ward MH. Geographically based investigation of prostate cancer mortality in four U.S. Northern Plain states. Am J Prev Med. 2006 Feb; 30(2 Suppl):S101-8. PMID: 16458784.
• Klassen AC, Curriero F, Kulldorff M, Alberg AJ, Platz EA, Neloms ST. Missing stage and grade in Maryland prostate cancer surveillance data, 1992-1997. Am J Prev Med. 2006 Feb; 30(2 Suppl):S77-87. PMID: 16458794.
• Kulldorff M and Information Management Systems Inc. SaTScan: Software for the spatial and space-time scan statistics [software]. 2006.
• Pozdnyakov V, Kulldorff M. Waiting times for patterns and a method of gambling teams. American Mathematical Monthly. 2006; 113:134-143.
• Kleinman K, Abrams A, Yih WK, Platt R, Kulldorff M. Assessing the utility of spatial surveillance: Detection of known outbreaks in real data. Statistics in Medicine. 2006; 25:755-769.
• Glaz J, Kulldorff M, Pozdnyakov V, Steele JM. Gambling teams and waiting times for patterns in two-stage Markov chains. Journal of Applied Probability. 2006; 43:127-140.
• Duczmal L, Kulldorff M, Huang L. Evaluation of spatial scan statistics for irregularly shaped clusters. Journal of Computational and Graphical Statistics. 2006; 15:428-442.
• Kulldorff M. Tests for spatial randomness adjusting for an underlying inhomogeneity: A general framework. Journal of the American Statistical Association. 2006; 101:1289-1305.
• Song C, Kulldorff M. Tango’s maximized excess events test with different weights. Int J Health Geogr. 2005 Dec 15; 4:32. PMID: 16356179; PMCID: PMC1343587.
• Johnson GD, Eidson M, Schmit K, Ellis A, Kulldorff M. Geographic prediction of human onset of West Nile virus using dead crow clusters: an evaluation of year 2002 data in New York State. Am J Epidemiol. 2006 Jan 15; 163(2):171-80. PMID: 16306307.
• Gupta RS, Shuman S, Taveras EM, Kulldorff M, Finkelstein JA. Opportunities for health promotion education in child care. Pediatrics. 2005 Oct; 116(4):e499-505. PMID: 16199677.
• Anderson KE, Kadlubar FF, Kulldorff M, Harnack L, Gross M, Lang NP, Barber C, Rothman N, Sinha R. Dietary intake of heterocyclic amines and benzo(a)pyrene: associations with pancreatic cancer. Cancer Epidemiol Biomarkers Prev. 2005 Sep; 14(9):2261-5. PMID: 16172241.
• Sinha R, Peters U, Cross AJ, Kulldorff M, Weissfeld JL, Pinsky PF, Rothman N, Hayes RB. Meat, meat cooking methods and preservation, and risk for colorectal adenoma. Cancer Res. 2005 Sep 01; 65(17):8034-41. PMID: 16140978.
• Nordin JD, Goodman MJ, Kulldorff M, Ritzwoller DP, Abrams AM, Kleinman K, Levitt MJ, Donahue J, Platt R. Simulated anthrax attacks and syndromic surveillance. Emerg Infect Dis. 2005 Sep; 11(9):1394-8. PMID: 16229768; PMCID: PMC3310627.
• Yih KW, Abrams A, Danila R, Green K, Kleinman K, Kulldorff M, Miller B, Nordin J, Platt R. Ambulatory-care diagnoses as potential indicators of outbreaks of gastrointestinal illness–Minnesota. MMWR Suppl. 2005 Aug 26; 54:157-62. PMID: 16177708.
• Cross AJ, Ward MH, Schenk M, Kulldorff M, Cozen W, Davis S, Colt JS, Hartge P, Cerhan JR, Sinha R. Meat and meat-mutagen intake and risk of non-Hodgkin lymphoma: results from a NCI-SEER case-control study. Carcinogenesis. 2006 Feb; 27(2):293-7. PMID: 16113054.
• Moore GE, Ward MP, Kulldorff M, Caldanaro RJ, Guptill LF, Lewis HB, Glickman LT. A space-time cluster of adverse events associated with canine rabies vaccine. Vaccine. 2005 Dec 01; 23(48-49):5557-62. PMID: 16112259.
• Sinha R, Kulldorff M, Gunter MJ, Strickland P, Rothman N. Dietary benzo[a]pyrene intake and risk of colorectal adenoma. Cancer Epidemiol Biomarkers Prev. 2005 Aug; 14(8):2030-4. PMID: 16103456.
• Kleinman KP, Abrams AM, Kulldorff M, Platt R. A model-adjusted space-time scan statistic with an application to syndromic surveillance. Epidemiol Infect. 2005 Jun; 133(3):409-19. PMID: 15962547; PMCID: PMC2870264.
• Gregorio DI, Dechello LM, Samociuk H, Kulldorff M. Lumping or splitting: seeking the preferred areal unit for health geography studies. Int J Health Geogr. 2005 Mar 23; 4(1):6. PMID: 15788100.
• Kulldorff M, Heffernan R, Hartman J, Assunção R, Mostashari F. A space-time permutation scan statistic for disease outbreak detection. PLoS Med. 2005 Mar; 2(3):e59. PMID: 15719066; PMCID: PMC548793.
• Klassen AC, Kulldorff M, Curriero F. Geographical clustering of prostate cancer grade and stage at diagnosis, before and after adjustment for risk factors. Int J Health Geogr. 2005 Jan 13; 4(1):1. PMID: 15649329.
• Kulldorff M. Scan statistics for geographical disease surveillance: An overview [book chapter]. Spatial and Syndromic Surveillance for Public Health. 2005.
• Klassen A, Kulldorff M, Curriero F. Geographical clustering of prostate cancer grade and stage at diagnosis, before and after adjustment for risk factors. International Journal of Health Geographics. 2005; 4:1.
• Pozdnyakov V, Glaz J, Kulldorff M, Steele M. A martingale approach to scan statistics. Annals of the Institute of Statistical Mathematics. 2005; 57:21-37.
• Yih K, Abrams A, Kleinman K, Kulldorff M, Nordin J, Platt R. Ambulatory care diagnoses as potential indicators of disease outbreaks: Gastrointestinal illness in Minnesota. Morbidity and Mortality Weekly Report. 2005; 54:Suppl: 157-62.
• Kulldorff M. Applied statistics research: ‘Challenging, valued and fun’[letter]. Institute of Mathematical Statistics Bulletin. 2005; 34:8-15.
• Anderson KE, Kadlubar FF, Kulldorff M, Harnack L, Gross M, Lang NP, Barber C, Rothman N, Sinha R. Dietary intake of heterocyclic amines and benzo(a)pyrene: Associations with pancreatic cancer. Cancer Epidemiology, Biomarkers and Prevention. 2005; 14:2261-2265.
• Gregorio DI, DeChello LM, Samociuk H, Kulldorff M. Lumping or splitting: Seeking the preferred arreal unit for health geography studies. International Journal of Health Geographic. 2005; 4:6.
• Gunter MJ, Probst-Hensch NM, Cortessis VK, Kulldorff M, Haile RW, Sinha R. Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control study. Carcinogenesis. 2005 Mar; 26(3):637-42. PMID: 15579480.
• Kulldorff M, Zhang Z, Hartman J, Heffernan R, Huang L, Mostashari F. Benchmark data and power calculations for evaluating disease outbreak detection methods. MMWR Suppl. 2004 Sep 24; 53:144-51. PMID: 15714644.
• Klassen AC, Curriero FC, Hong JH, Williams C, Kulldorff M, Meissner HI, Alberg A, Ensminger M. The role of area-level influences on prostate cancer grade and stage at diagnosis. Prev Med. 2004 Sep; 39(3):441-8. PMID: 15313082.
• Joseph Sheehan T, DeChello LM, Kulldorff M, Gregorio DI, Gershman S, Mroszczyk M. The geographic distribution of breast cancer incidence in Massachusetts 1988 to 1997, adjusted for covariates. Int J Health Geogr. 2004 Aug 03; 3(1):17. PMID: 15291960.
• Prestwood KM, Unson C, Kulldorff M, Cushman M. The effect of different doses of micronized 17beta-estradiol on C-reactive protein, interleukin-6, and lipids in older women. J Gerontol A Biol Sci Med Sci. 2004 Aug; 59(8):827-32. PMID: 15345733.
• Fang Z, Kulldorff M, Gregorio DI. Brain cancer mortality in the United States, 1986 to 1995: a geographic analysis. Neuro Oncol. 2004 Jul; 6(3):179-87. PMID: 15279710; PMCID: PMC1872002.
• Heffernan R, Mostashari F, Das D, Karpati A, Kulldorff M, Weiss D. Syndromic surveillance in public health practice, New York City. Emerg Infect Dis. 2004 May; 10(5):858-64. PMID: 15200820.
• Mathew A, Peters U, Chatterjee N, Kulldorff M, Sinha R. Fat, fiber, fruits, vegetables, and risk of colorectal adenomas. Int J Cancer. 2004 Jan 10; 108(2):287-92. PMID: 14639617.
• Kulldorff M, Zhang Z, Hartman J, Heffernan R, Huang L, Mostashari F. Evaluating disease outbreak detection methods: Benchmark data and power calculations. Morbidity and Mortality Weekly Report. 2004; 53:144-151.
• Sheehan TJ, DeChello LM, Kulldorff M, Gregorio DI, Gershman S, Mroszczyk M. The geographic distribution of breast cancer incidence in Massachusetts 1988-1997, adjusted for covariates. International Journal of Health Geographics. 2004; 3:17.
• Prestwood KM, Unson C, Kulldorff M, Cushman M. The effect of different doses of micronized 17b-estradiol on C-reactive protein, interleukin-6 and lipids in older women. Journal of Gerontology: Medical Sciences. 2004; 59:827-832.
• Peters U, Sinha R, Bell DA, Rothman N, Grant DJ, Watson MA, Kulldorff M, Brooks LR, Warren SH, DeMarini DM. Urinary mutagenesis and fried red meat intake: influence of cooking temperature, phenotype, and genotype of metabolizing enzymes in a controlled feeding study. Environ Mol Mutagen. 2004; 43(1):53-74. PMID: 14743346.
• Gregorio DI, Kulldorff M, Sheehan TJ, Samociuk H. Geographic distribution of prostate cancer incidence in the era of PSA testing, Connecticut, 1984 to 1998. Urology. 2004 Jan; 63(1):78-82. PMID: 14751353.
• Song C, Kulldorff M. Power evaluation of disease clustering tests. Int J Health Geogr. 2003 Dec 19; 2(1):9. PMID: 14687424.
• Fang LQ, Cao WC, Dun Z, Wu XM, Sun PY, Kulldorff M, Wang BC, Yang H, Li XW. [Spatial analysis on the distribution of hemorrhagic fever with renal syndrome by geographic information system in Haidian district, Beijing]. Zhonghua Liu Xing Bing Xue Za Zhi. 2003 Nov; 24(11):1020-3. PMID: 14687504.
• Prestwood KM, Kenny AM, Kleppinger A, Kulldorff M. Ultralow-dose micronized 17beta-estradiol and bone density and bone metabolism in older women: a randomized controlled trial. JAMA. 2003 Aug 27; 290(8):1042-8. PMID: 12941676.
• Mostashari F, Kulldorff M, Hartman JJ, Miller JR, Kulasekera V. Dead bird clusters as an early warning system for West Nile virus activity. Emerg Infect Dis. 2003 Jun; 9(6):641-6. PMID: 12781002; PMCID: PMC3000152.
• Kulldorff M, Fang Z, Walsh SJ. A tree-based scan statistic for database disease surveillance. Biometrics. 2003 Jun; 59(2):323-31. PMID: 12926717.
• Peters U, Sinha R, Chatterjee N, Subar AF, Ziegler RG, Kulldorff M, Bresalier R, Weissfeld JL, Flood A, Schatzkin A, Hayes RB. Dietary fibre and colorectal adenoma in a colorectal cancer early detection programme. Lancet. 2003 May 03; 361(9368):1491-5. PMID: 12737857.
• Kulldorff M. Spatial epidemiology, methods and applications [book review]. Statistics in Medicine. 2003; 2381-2382.
• Kulldorff M, Tango T, Park PJ. Power comparisons for disease clustering tests. Computational Statistics and Data Analysis. 2003; 42:665-684.
• Kleppinger A, Litt M, Kulldorff M, Unson C, Judge JO. Health perceptions as predictors of exercise adherence in older women. European Journal of Sport Science. 2003; 3:1-15.
• Kulldorff M. Methods comparisons. Re: ‘Local clustering in breast, lung and colorectal cancer in Long Island, New York’, by Jacquez GM, Greiling DA [commentary]. International Journal of Health Geographics. 2003; 2:3.
• Kulldorff M. SaTScan User Guide [software manual]- www.satscan.org, v3.1, 4.0 2003; v5.0, 5.1:2004. 2003.
• Oncken C, Prestwood K, Cooney JL, Unson C, Fall P, Kulldorff M, Raisz LG. Effects of smoking cessation or reduction on hormone profiles and bone turnover in postmenopausal women. Nicotine Tob Res. 2002 Nov; 4(4):451-8. PMID: 12521404.
• Anderson KE, Sinha R, Kulldorff M, Gross M, Lang NP, Barber C, Harnack L, DiMagno E, Bliss R, Kadlubar FF. Meat intake and cooking techniques: associations with pancreatic cancer. Mutat Res. 2002 Sep 30; 506-507:225-31. PMID: 12351162.
• Jemal A, Kulldorff M, Devesa SS, Hayes RB, Fraumeni JF. A geographic analysis of prostate cancer mortality in the United States, 1970-89. Int J Cancer. 2002 Sep 10; 101(2):168-74. PMID: 12209994.
• Gregorio DI, Kulldorff M, Barry L, Samociuk H. Geographic differences in invasive and in situ breast cancer incidence according to precise geographic coordinates, Connecticut, 1991-95. Int J Cancer. 2002 Jul 10; 100(2):194-8. PMID: 12115569.
• Kulldorff M. Geographical distribution of sporadic Creutzfeldt-Jakob Disease in France. Int J Epidemiol. 2002 Apr; 31(2):495-6. PMID: 11980825.
• Ishibe N, Sinha R, Hein DW, Kulldorff M, Strickland P, Fretland AJ, Chow WH, Kadlubar FF, Lang NP, Rothman N. Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas. Pharmacogenetics. 2002 Mar; 12(2):145-50. PMID: 11875368.
• Fang Z, Smith JA, Kleppinger A, Reisine ST, Emerson D, Kulldorff M. Retrospective evaluation and adjustment of dual energy X-ray absorptiometry measurements for bone mineral density research studies. J Clin Densitom. 2002; 5(4):421-33. PMID: 12665643.
• Gregorio DI, Kulldorff M, Barry L, Samocuik H, Zarfos K. Geographical differences in primary therapy for early-stage breast cancer. Ann Surg Oncol. 2001 Dec; 8(10):844-9. PMID: 11776501.
• Sinha R, Kulldorff M, Chow WH, Denobile J, Rothman N. Dietary intake of heterocyclic amines, meat-derived mutagenic activity, and risk of colorectal adenomas. Cancer Epidemiol Biomarkers Prev. 2001 May; 10(5):559-62. PMID: 11352869.
• Kulldorff M. Ett heltäckande svenskt släktträd (in Swedish) [letter]. Släkthistoriskt Forum. 2001; 4:6-7.
• Kulldorff M. Prospective time-periodic geographical disease surveillance using a scan statistic. Journal of the Royal Statistical Society. 2001; A164:61-72.
• Kulldorff M, Sinha R, Chow WH, Rothman N. Comparing odds ratios for nested subsets of dietary components. Int J Epidemiol. 2000 Dec; 29(6):1060-4. PMID: 11101548.
• Prestwood KM, Kenny AM, Unson C, Kulldorff M. The effect of low dose micronized 17ss-estradiol on bone turnover, sex hormone levels, and side effects in older women: a randomized, double blind, placebo-controlled study. J Clin Endocrinol Metab. 2000 Dec; 85(12):4462-9. PMID: 11134094.
• Sheehan TJ, Gershman ST, MacDougall LA, Danley RA, Mroszczyk M, Sorensen AM, Kulldorff M. Geographic assessment of breast cancer screening by towns, zip codes, and census tracts. J Public Health Manag Pract. 2000 Nov; 6(6):48-57. PMID: 18019960.
• Jemal A, Devesa S, Kulldorff M, Hayes R, Fraumeni J. Geographic variation in prostate cancer mortality rates among white males in the united states. Ann Epidemiol. 2000 Oct 01; 10(7):470. PMID: 11018400.
• Talbot TO, Kulldorff M, Forand SP, Haley VB. Evaluation of spatial filters to create smoothed maps of health data. Stat Med. 2000 Sep 15-30; 19(17-18):2399-408. PMID: 10960861.
• Sinha R, Gustafson DR, Kulldorff M, Wen WQ, Cerhan JR, Zheng W. 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, a carcinogen in high-temperature-cooked meat, and breast cancer risk. J Natl Cancer Inst. 2000 Aug 16; 92(16):1352-4. PMID: 10944558.
• Kulldorff M, McShane LM, Schatzkin A, Freedman LS, Wargovich MJ, Woods C, Purewal M, Burt RW, Lawson M, Mateski DJ, Lanza E, Corle DK, O’Brien B, Moler J. Measuring cell proliferation in the rectal mucosa. comparing bromodeoxyuridine (BrdU) and proliferating cell nuclear antigen (PCNA) assays. J Clin Epidemiol. 2000 Aug; 53(8):875-83. PMID: 10942872.
• Subar AF, Midthune D, Kulldorff M, Brown CC, Thompson FE, Kipnis V, Schatzkin A. Evaluation of alternative approaches to assign nutrient values to food groups in food frequency questionnaires. Am J Epidemiol. 2000 Aug 01; 152(3):279-86. PMID: 10933275.
• Sinha R, Kulldorff M, Swanson CA, Curtin J, Brownson RC, Alavanja MC. Dietary heterocyclic amines and the risk of lung cancer among Missouri women. Cancer Res. 2000 Jul 15; 60(14):3753-6. PMID: 10919646.
• Velie E, Kulldorff M, Schairer C, Block G, Albanes D, Schatzkin A. Dietary fat, fat subtypes, and breast cancer in postmenopausal women: a prospective cohort study. J Natl Cancer Inst. 2000 May 17; 92(10):833-9. PMID: 10814679.
• Sheehan TJ, Gershman ST, MacDougal L, Danley R, Mrosszczyk M, Sorensen AM, Kulldorff M. Geographical surveillance of breast cancer screening by tracts, towns and zip codes. Journal of Public Health Management and Practice. 2000; 6:48-57.
• Kulldorff M. Mathematical formula for Swartz’ Entropy Test Statistic. Health Place. 1999 Dec; 5(4):313. PMID: 11066903.
• Velie EM, Block G, Shaw GM, Samuels SJ, Schaffer DM, Kulldorff M. Maternal supplemental and dietary zinc intake and the occurrence of neural tube defects in California. Am J Epidemiol. 1999 Sep 15; 150(6):605-16. PMID: 10490000.
• Sinha R, Chow WH, Kulldorff M, Denobile J, Butler J, Garcia-Closas M, Weil R, Hoover RN, Rothman N. Well-done, grilled red meat increases the risk of colorectal adenomas. Cancer Res. 1999 Sep 01; 59(17):4320-4. PMID: 10485479.
• Kulldorff M, Hjalmars U. The Knox method and other tests for space-time interaction. Biometrics. 1999 Jun; 55(2):544-52. PMID: 11318212.
• Kulldorff M, Graubard B, Velie E. The P-value and P-value function. Epidemiology. 1999 May; 10(3):345-7. PMID: 10230850.
• Hjalmars U, Kulldorff M, Wahlqvist Y, Lannering B. Increased incidence rates but no space-time clustering of childhood astrocytoma in Sweden, 1973-1992: a population-based study of pediatric brain tumors. Cancer. 1999 May 01; 85(9):2077-90. PMID: 10223251.
• Kulldorff M. Geographic information systems (GIS) and community health: some statistical issues. J Public Health Manag Pract. 1999 Mar; 5(2):100-6. PMID: 10537802.
• Lawson AB, Kulldorff M. A review of cluster detection methods [book chapter]. Advanced Methods of Disease Mapping and Risk Assessment for Public Health Decision Making. 1999; 99-110.
• Kulldorff M. Re: An entropy-based algorithm for detecting clusters of cases and controls and its comparison with a method using nearest neighbors [letter]. Health and Place. 1999; 5:313.
• Khanna A, Kulldorff M. A generalization of the mutual fund theorem. Finance adn Stochastics. 1999; 3:167-185.
• Kulldorff M. An isotonic spatial scan statistic for geographical disease surveillance. Journal of the National Institute of Public Health. 1999; 48:94-101.
• Kulldorff M. Spatial scan statistics: Models, calculations and applications [book chapter]. Scan Statistics and Applications. 1999; 303-322.
• Kulldorff M. Statistical evaluation of disease cluster alarms [book chapter]. Advanced Methods of Disease Mapping and Risk Assessment for Public Health Decision Making. 1999; 143-149.
• Sinha R, Kulldorff M, Curtin J, Brown CC, Alavanja MC, Swanson CA. Fried, well-done red meat and risk of lung cancer in women (United States). Cancer Causes Control. 1998 Dec; 9(6):621-30. PMID: 10189048.
• Kulldorff M, Athas WF, Feurer EJ, Miller BA, Key CR. Evaluating cluster alarms: a space-time scan statistic and brain cancer in Los Alamos, New Mexico. Am J Public Health. 1998 Sep; 88(9):1377-80. PMID: 9736881; PMCID: PMC1509064.
• McShane LM, Kulldorff M, Wargovich MJ, Woods C, Purewal M, Freedman LS, Corle DK, Burt RW, Mateski DJ, Lawson M, Lanza E, O’Brien B, Lake W, Moler J, Schatzkin A. An evaluation of rectal mucosal proliferation measure variability sources in the polyp prevention trial: can we detect informative differences among individuals’ proliferation measures amid the noise? Cancer Epidemiol Biomarkers Prev. 1998 Jul; 7(7):605-12. PMID: 9681529.
• Kulldorff M, Rand K, Williams G, Williams G, DeFrancesco D. SaTScan: Software for the spatial and space-time scan statistics [software]- Volume 2.0, 2.1. 1998.
• Kulldorff M. Re: Some methods for investigating spatial clustering with epidemiological applications [letter]. Journal of the Royal Statistical Society. 1998; A161:273.
• Kulldorff M. Statistical methods for spatial epidemiology: Tests for randomness [book chapter]. GIS and Health. 1998; 49-62.
• Swanson CA, Brown CC, Sinha R, Kulldorff M, Brownson RC, Alavanja MC. Dietary fats and lung cancer risk among women: the Missouri Women’s Health Study (United States) Cancer Causes Control. 1997 Nov; 8(6):883-93. PMID: 9427431.
• Kulldorff M, Feuer EJ, Miller BA, Freedman LS. Breast cancer clusters in the northeast United States: a geographic analysis. Am J Epidemiol. 1997 Jul 15; 146(2):161-70. PMID: 9230778.
• Kulldorff M. Teaching the foundations of statistics: A helpful figure. InterStat. 1997.
• Kulldorff M. A spatial scan statistic. Communications in Statistics: Theory and Methods. 1997; 26:1481-1496.
• Kulldorff M, Rand K, Williams G, Williams G, DeFrancesco D. SaTScan: Software for the spatial and space-time scan statistics [software] – Volume 1. 1997.
• Hjalmars U, Kulldorff M, Gustafsson G, Nagarwalla N. Childhood leukaemia in Sweden: using GIS and a spatial scan statistic for cluster detection. Stat Med. 1996 Apr 15-May 15; 15(7-9):707-15. PMID: 9132898.
• Abrahamsson PA, Adami HO, Taube A, Kim KM, Zelen M, Kulldorff M. Re: Long-term survival and mortality in prostate cancer treated with noncurative intent [letter]. Journal of Urology. 1996; 155:296-298.
• Abrahamsson A, Adami HO, Taube A, Kim K, Zelen M, Kulldorff M. Re: Long-term survival and mortality in prostate cancer treated with noncurative intent. J Urol. 1996 Jan; 155(1):296-8. PMID: 7490872.
• Kulldorff M, Nagarwalla N. Spatial disease clusters: detection and inference. Stat Med. 1995 Apr 30; 14(8):799-810. PMID: 7644860.
• Hjalmars U, Kulldorff M, Gustafsson G. Risk of acute childhood leukaemia in Sweden after the Chernobyl reactor accident. Swedish Child Leukaemia Group. BMJ. 1994 Jul 16; 309(6948):154-7. PMID: 8044093; PMCID: PMC2540704.
• Kulldorff M. Optimal control of favorable games with a time limit. SIAM Journal on Control and Optimization. 1993; 31:52-69.
• Kulldorff M. A survey of statistical journals [review]. The Institute of Mathematical Statistics Bulletin. 1992; 21:399-407.
• Kulldorff M. Optimal control of favorable games with a time limit [PhD Thesis]. 1989.
• Kulldorff M. Tandem queues with blocking [M.Sc. Thesis]. 1986.
• Kulldorff M. A study of a queuing system where transfer from one queue to another is allowed (in Swedish)[B.Sc. Thesis]. 1984.